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Ronny Allan – Living with Neuroendocrine Cancer

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  • About
    • Join the Support Group
    • Recommendations
    • My Diagnosis and Treatment
      • My Neuroendocrine Cancer Surgery – Small Intestine NET, a patient experience (part 1)
      • My Neuroendocrine Cancer Surgery – a patient experience (part 2)
      • My liver rescetion
      • My lymphadenectomy
    • Ronny’s Video Presentations
    • Health Union Patient Leader
    • Disclaimer
    • Award Winning Blog
  • A spotlight on NENs
    • A spotlight on NENs – Types
      • A spotlight on Small Intestine Neuroendocrine Tumours
      • A spotlight on Appendiceal Neuroendocrine Neoplasms
      • A spotlight on duodenal Neuroendocrine Neoplasms (dNENs)
      • A spotlight on Rectal Neuroendocrine Neoplasms
      • A Spotlight on Lung Neuroendocrine Neoplasms
      • Neuroendocrine Tumours: a spotlight on Pheochromocytoma and Paraganglioma
      • A spotlight on Grade 3 (High grade) Neuroendocrine Neoplasms
    • A spotlight on NENs – Syndromes
      • A Spotlight on Neuroendocrine Cancer Syndromes – Carcinoid Syndrome
    • A Spotlight on NENs – Testing
      • Tumour markers and Hormone Levels
      • A spotlight on Chromogranin A
      • A spotlight on 5-HIAA
      • The NETest® – a Chromogranin A replacement and more?
  • Epidemiology
    • Neuroendocrine tumors are uncommon but definitely not rare
    • Neuroendocrine Neoplasms – not as rare as you think
    • The Invisible NET Patient Population 
    • Genetics
      • Neuroendocrine Neoplasms (NEN) – genetic related syndromes
      • A spotlight on Multiple Endocrine Neoplasia (MEN)
  • NET Guidelines
  • Diagnosis and Surveillance
    • Neuroendocrine Neoplasms – Classification, Grade and Stage
    • A spotlight on Gastric Neuroendocrine Neoplasms
    • Where to find a NET Specialist worldwide
    • 10 questions to ask your doctor
    • Diagnosing the Undiagnosed
    • A needle in a haystack?
    • Marker Tests
    • Syndromes and Symptoms
      • I bet my flush beats yours?
      • Neuroendocrine Cancer – the diarrhea jigsaw
      • The Syndromes of Neuroendocrine Cancer – Early Signs of a Late Diagnosis
      • Hormones
      • Neuroendocrine Cancer: Clinical Esoterica
      • Gallium 68 PET Scans – Into the Unknown
      • Serotonin – the NET effect
      • Cancer-related fatigue (CRF) – Neuroendocrine Cancer
      • Imaging
        • Neuroendocrine Cancer – If you can see it, you can detect it!
        • Ga68 PET Scan – a game changer?
        • Neuroendocrine Tumours – now you see them, now you don’t!
        • Detectnet™ (64Cu-DOTATATE) – an expansion of the Somatostatin Receptor PET Imaging for Neuroendocrine Cancer
        • Understanding your Somatostatin Receptor (SSTR) PET/CT Scan Results
  • Treatments
    • Treatment – a summary for patients
    • Surgery
      • Surgery for Neuroendocrine Neoplasms – to cut or not to cut?
      • Surgery for NETs – Chop Chop
      • Surgery is risky but so is driving a car
      • Small intestine, large surgery
      • Pancreatic Neuroendocrine Tumours – surgical decisions
      • Neuroendocrine Cancer – my liver surgery
    • Liver Embolization (bland, chemo, radio)
    • Somatostatin Receptors
    • PRRT
      • Peptide Receptor Radionuclide Therapy (PRRT)
      • Selecting patients and the Challenges of Evaluating Response to PRRT in GEPNETs: The Present and the Future
    • Somatostatin Analogues
      • Somatostatin Analogues for Neuroendocrine Cancer: Lanreotide and Octreotide
      • Lanreotide – it’s calling the shots!
      • At home with Lanreotide (….and Octreotide)
      • Somatostatin Analogues and delivery methods in the pipeline
    • Everolimus (Afinitor)
    • Sunitinib (Sutent)
    • Chemotherapy
    • Telotristat Ethyl (XERMELO®)
  • Diet and Nutrition
    • Q. The best diet for Neuroendocrine Cancer? A. The one that works for you.
    • Article 1 – Vitamin and Mineral Challenges
    • Article 2 – Gastrointestinal Malabsorption
    • Article 3 – Gut Health
    • Article 4 – Food for Thought?
    • Article 5 – Pancreatic Enzyme Replacement Therapy (PERT)
    • Article 6 – featuring the 2020 video series by Tara Whyand RD
    • The trouble with the NET (Part 5) – Cancer Diet Myths
    • Lactose intolerance – the NET Effect
    • Fructose intolerance – the NET Effect
    • Low FODMAPs – The NET Effect
    • Low and High Residue Foods
  • Clinical Trials and Research
  • Awareness Posts
    • The Trouble with the NET Series
    • The NET Effect Series
    • All Awareness Posts
  • Glossary of Terms (A to Z)
  • Home Page
  • About
    • Join the Support Group
    • Recommendations
    • My Diagnosis and Treatment
      • My Neuroendocrine Cancer Surgery – Small Intestine NET, a patient experience (part 1)
      • My Neuroendocrine Cancer Surgery – a patient experience (part 2)
      • My liver rescetion
      • My lymphadenectomy
    • Ronny’s Video Presentations
    • Health Union Patient Leader
    • Disclaimer
    • Award Winning Blog
  • A spotlight on NENs
    • A spotlight on NENs – Types
      • A spotlight on Small Intestine Neuroendocrine Tumours
      • A spotlight on Appendiceal Neuroendocrine Neoplasms
      • A spotlight on duodenal Neuroendocrine Neoplasms (dNENs)
      • A spotlight on Rectal Neuroendocrine Neoplasms
      • A Spotlight on Lung Neuroendocrine Neoplasms
      • Neuroendocrine Tumours: a spotlight on Pheochromocytoma and Paraganglioma
      • A spotlight on Grade 3 (High grade) Neuroendocrine Neoplasms
    • A spotlight on NENs – Syndromes
      • A Spotlight on Neuroendocrine Cancer Syndromes – Carcinoid Syndrome
    • A Spotlight on NENs – Testing
      • Tumour markers and Hormone Levels
      • A spotlight on Chromogranin A
      • A spotlight on 5-HIAA
      • The NETest® – a Chromogranin A replacement and more?
  • Epidemiology
    • Neuroendocrine tumors are uncommon but definitely not rare
    • Neuroendocrine Neoplasms – not as rare as you think
    • The Invisible NET Patient Population 
    • Genetics
      • Neuroendocrine Neoplasms (NEN) – genetic related syndromes
      • A spotlight on Multiple Endocrine Neoplasia (MEN)
  • NET Guidelines
  • Diagnosis and Surveillance
    • Neuroendocrine Neoplasms – Classification, Grade and Stage
    • A spotlight on Gastric Neuroendocrine Neoplasms
    • Where to find a NET Specialist worldwide
    • 10 questions to ask your doctor
    • Diagnosing the Undiagnosed
    • A needle in a haystack?
    • Marker Tests
    • Syndromes and Symptoms
      • I bet my flush beats yours?
      • Neuroendocrine Cancer – the diarrhea jigsaw
      • The Syndromes of Neuroendocrine Cancer – Early Signs of a Late Diagnosis
      • Hormones
      • Neuroendocrine Cancer: Clinical Esoterica
      • Gallium 68 PET Scans – Into the Unknown
      • Serotonin – the NET effect
      • Cancer-related fatigue (CRF) – Neuroendocrine Cancer
      • Imaging
        • Neuroendocrine Cancer – If you can see it, you can detect it!
        • Ga68 PET Scan – a game changer?
        • Neuroendocrine Tumours – now you see them, now you don’t!
        • Detectnet™ (64Cu-DOTATATE) – an expansion of the Somatostatin Receptor PET Imaging for Neuroendocrine Cancer
        • Understanding your Somatostatin Receptor (SSTR) PET/CT Scan Results
  • Treatments
    • Treatment – a summary for patients
    • Surgery
      • Surgery for Neuroendocrine Neoplasms – to cut or not to cut?
      • Surgery for NETs – Chop Chop
      • Surgery is risky but so is driving a car
      • Small intestine, large surgery
      • Pancreatic Neuroendocrine Tumours – surgical decisions
      • Neuroendocrine Cancer – my liver surgery
    • Liver Embolization (bland, chemo, radio)
    • Somatostatin Receptors
    • PRRT
      • Peptide Receptor Radionuclide Therapy (PRRT)
      • Selecting patients and the Challenges of Evaluating Response to PRRT in GEPNETs: The Present and the Future
    • Somatostatin Analogues
      • Somatostatin Analogues for Neuroendocrine Cancer: Lanreotide and Octreotide
      • Lanreotide – it’s calling the shots!
      • At home with Lanreotide (….and Octreotide)
      • Somatostatin Analogues and delivery methods in the pipeline
    • Everolimus (Afinitor)
    • Sunitinib (Sutent)
    • Chemotherapy
    • Telotristat Ethyl (XERMELO®)
  • Diet and Nutrition
    • Q. The best diet for Neuroendocrine Cancer? A. The one that works for you.
    • Article 1 – Vitamin and Mineral Challenges
    • Article 2 – Gastrointestinal Malabsorption
    • Article 3 – Gut Health
    • Article 4 – Food for Thought?
    • Article 5 – Pancreatic Enzyme Replacement Therapy (PERT)
    • Article 6 – featuring the 2020 video series by Tara Whyand RD
    • The trouble with the NET (Part 5) – Cancer Diet Myths
    • Lactose intolerance – the NET Effect
    • Fructose intolerance – the NET Effect
    • Low FODMAPs – The NET Effect
    • Low and High Residue Foods
  • Clinical Trials and Research
  • Awareness Posts
    • The Trouble with the NET Series
    • The NET Effect Series
    • All Awareness Posts
  • Glossary of Terms (A to Z)

Tag: Talazoparib

Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer. (BNM-673, trade name Talzenna) is approved by FDA/UK NHS and many other countries as a targeted therapy for certain cancers, developed by Pfizer. It is a PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair.

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  • Talazoparib
Study of Lu-177-DOTATATE (Lutathera) in Combination With PARP Inhibitors in Inoperable/Metastatic Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET)
Clinical Trials and ResearchLutathera, Olaparib, PARP Inhibitor, Peptide receptor radionuclide therapy (PRRT), PRRT, Talazoparib

Study of Lu-177-DOTATATE (Lutathera) in Combination With PARP Inhibitors in Inoperable/Metastatic Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET)

By Ronny Allan Oct 06, 2022 3 Comments

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  • Next Generation Total-Body PET/CT: Challenges and Opportunities
  • Phase 1/2 Trial Evaluating CRN09682 for the Treatment of Neuroendocrine Tumors and Other Somatostatin Receptor 2-Expressing Tumors
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