
After a few months of introducing C-19 vaccines, many cases of false-positive lymph nodes were reported on nuclear PET scans, some of which led to unnecessary biopsies and unnecessary worry for the patients concerned. According to Mayo Clinic, the positive nodes were on the same side as the vaccine shot in the cases where the […]

What is PRRT? I’m guessing most of my readers know what Peptide Receptor Radiotherapy (PRRT) is. But for those new to this field, read more here What is Triapine? Triapine is a ribonucleotide reductase (RNR) inhibitor, I.e. it helps repair DNA. When I research this drug, I can see it is used in numerous examples […]

What is CAPTEM? Capecitabine is an oral drug used alone or with other drugs to treat certain types of colorectal cancer and breast cancer. It is also being studied in the treatment of other types of cancer including in combination with a second drug. Capecitabine is taken up by cancer cells and breaks down into […]

When I read comments in my private Facebook community group, I can see that many people do get concerned about upcoming scans and other rest results. I think the imaging results cause the most angst because those are probably the most telling results someone with Neuroendocrine Cancer will get. Has it grown, has it shrunk? […]

Whenever I post about a new trial or study, some people get excited without understanding that these new treatments and capabilities can very often take years to come to fruition and it’s also possible that clinical trials can be halted, or that national approval agencies will not approve the final product. Please bear that in […]
Ronny-
Immunotherapy on the site?
I was diagnosed with stage 4 pancreatic NET mets to liver in Jan 2019. After a few weeks with a 3-6 mo survival diagnosis some additional tumor analysis found they were Hi-MSI tumors -eligible to be treated with recently approved (for all Hi MSI solid tumors) immunotherapy.
I had great results being treated with ipilumumab + nivolumab for 24 mos. Tumors shrunk to about 10% of the original mass and then were stable for a couple more months. Once the tumors started growing (slowly) again, I came off the original treatment and have been on investigational immunotherapy since. First trail was successful for 3-6 mos. Now I’m onto the 2nd trial and feeling better again.
With an FDA approved immunotherapy for Hi-MSI NETs, suggest it would be useful to have info about immunotherapy on your site. I was treated at MD Anderson in Houston.
The team at MD Anderson almost immediately did tumor analysis that flagged the biomarkers which showed immunotherapy would likely be effective. Suspect not all patients have that good fortune.
Let me know if I can help.
-P
What is your grade and differentation?
The immunotherapy experience with Neuroendocrine Neoplasms is not great, there’s always outliers of course.