Neuroendocrine Tumors: Targeted Therapies – Update from NET Specialist Diane Reidy-Lagunes, MD, Memorial Sloan-Kettering Cancer Center – August 2021

Background.  For those who want a quick run through of Neuroendocrine Tumors from diagnosis to selection of treatment, about the treatments themselves plus what is the Future Directions in the Management of Neuroendocrine Tumors.  There are 8 episodes, and each is around 3-5 minutes long. I personally found them very useful and in a language understandable to patients. 

Great job by OncLive and Dr Reidy-Lagunes! 

Diane Reidy-Lagunes, MD, provides an overview of neuroendocrine tumors, along with specific considerations for optimal diagnosis and prognostication. 

Understanding the Diagnosis and Prognosis of Neuroendocrine Tumors (

Expert insight on the pathogenesis of neuroendocrine tumors and the best use of molecular testing to inform treatment decisions.

Neuroendocrine Tumor Pathogenesis and Molecular Testing (

Standard treatment pathways for patients with neuroendocrine tumors involving systemic therapy, surgery, and radiation.

An Overview of Treatment Approaches for Neuroendocrine Tumors (

A detailed explanation on how disease and patient factors inform selection from the treatment armamentarium for neuroendocrine tumors.

Neuroendocrine Tumors: Factors That Inform Therapy Selection (

Diane Reidy-Lagunes, MD, outlines goals of therapy and selection of systemic therapy for patients with neuroendocrine tumors.

Systemic Therapy for Advanced Neuroendocrine Tumors (

Expert reflections on VEGF-targeted therapy’s role in the treatment of patients with neuroendocrine tumors.

Advanced Neuroendocrine Tumors: VEGF-Targeted Therapies (

Considerations for use of surufatinib in patients with neuroendocrine tumors in light of the SANET-p and SANET-ep clinical trials.

Advanced Neuroendocrine Tumors: Clinical Trials With Surufatinib (

Looking toward the future management of neuroendocrine tumors, Diane Reidy-Lagunes, MD, shares insight on possible therapy evolutions and ongoing unmet needs.

Future Directions in the Management of Neuroendocrine Tumors (

Most of this is pretty standard knowledge across the NET Specialist community.  One thing I would add is that Dr Reidy-Lagunes talked in at least one of the videos about her own approach to treating NET patients and this may differ in other NET centers.

I hope you enjoyed watching these short but very informative videos? 

Thanks for reading.


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