Neuroendocrine Cancer – Liver directed therapy

Neuroendocrine Cancer – Liver directed therapy

May 2026. Updated to include Transarterial Chemoperfusion (TACP) Neuroendocrine Neoplasms (NENs) present complex challenges to diagnosis and treatment. Even in metastatic cases spreading to the liver, there are some important differences compared to the more common types of gastrointestinal tumours and pancreatic adenocarcinomas, e.g. their sometimes-indolent nature and their ability to oversecrete hormones causing distinct clinical syndromes. Also, the tumours are known to be highly vascular which is a feature where growth inhibition and symptom relief may be achieved by specific 'blocking' agents - this is particularly the case with liver metastases in well-differentiated Neuroendocrine Tumours (NETs). Spread to the liver…
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Cancer Ablation

Cancer Ablation

What is Cancer Ablation? This is a minimally invasive surgical method to treat solid cancers. More modern types of ablative style treatments may be described as non-invasive.  With conventional ablation, special probes are used to “burn” or “freeze” cancers. Computed Tomography (CT), Ultrasound (US) or Magnetic Resonance Imaging (MRI) is used to guide and position the needle probe into the tumour. This requires only a tiny hole, usually less than 3 mm via which the probe is introduced. When the probe is within the cancer it is attached to a generator which “burns” or “freezes” the cancer.  “Burning” refers to…
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Histotripsy:  A new technique that treats cancer using soundwaves – the story so far

Histotripsy: A new technique that treats cancer using soundwaves – the story so far

First published on April 25, 2022.   Updated regularly.  Last update 2nd Nov 2026. If you just want to know what Histotripsy is, just head straight down to "Original Article" section 2nd  November 2026.  Singapore - HistoSonics histotripsy expands into Singapore, with potential implications for Australia HistoSonics has announced regulatory approval in Singapore for its Edison Histotripsy System, continuing the international expansion of its non-invasive technology for destroying liver tumours. Histotripsy uses focused ultrasound energy to mechanically destroy and liquefy targeted tumour tissue, without surgical incisions. The technology has previously received US FDA De Novo clearance, and clinical studies have included…
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