14Jan 2023 by Ronny Allan No Comments
Cancer Ablation

Cancer Ablation

Clinical Trials and Research, Patient Advocacy, Treatment
What is Cancer Ablation? This is a minimally invasive surgical method to treat solid cancers. Special probes are used to “burn” or “freeze” cancers. Computed Tomography (CT), Ultrasound (US) or Magnetic Resonance Imaging (MRI) is used to guide and position the needle probe into the tumour. This requires only a tiny hole, usually less than 3 mm via which the probe is introduced. When the probe is within the cancer it is attached to a generator which “burns” or “freezes” the cancer.  “Burning” refers to increasing the temperature of the tumour to such a level that cancer cells die. This is usually achieved by radio frequency probes, referring to the type of energy used to increase the temperature. “Freezing” refers to cryoablation which decreases the temperature to -40 C (-40…
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25Apr 2022 by Ronny Allan 2 Comments
Histotripsy: A new technique which destroys cancer using soundwaves

Histotripsy: A new technique which destroys cancer using soundwaves

Clinical Trials and Research, Treatment
Illustration of histotripsy technology. Image courtesy of Medicine at Michigan Magazine. BREAKING NEWS 9TH OCT 2023 - US FDA APPROVES THE USE OF HISTOTRIPSY IN HUMANS FOR LIVER TREATMENTRead here Tumor-destroying sound waves receive FDA approval for liver treatment in humans | University of Michigan News (umich.edu)..... and then read about Histotripsy and the clinical trials belowORIGINAL ARTICLE FOLLOWS ......A new technique that destroys cancer using soundwaves.  It also spurs the immune system to kill off any of the tumour left behind, scientists have revealed. The non-invasive treatment only needs to be partially effective to stop the cancer spreading.It is currently being tested on human liver cancers in the US and Europe following successful trials in rats. The team from the University of Michigan showed the non-invasive sound technology is…
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22Jan 2020 by Ronny Allan 11 Comments
Neuroendocrine Cancer – Liver directed therapy

Neuroendocrine Cancer – Liver directed therapy

Treatment
Neuroendocrine Neoplasms (NENs) present complex challenges to diagnosis and treatment. Even in metastatic cases spreading to the liver, there are some important differences compared to the more common types of gastrointestinal tumours and pancreatic adenocarcinomas, e.g. their sometimes-indolent nature and their ability to oversecrete hormones causing distinct clinical syndromes. Also, the tumours are known to be highly vascular which is a feature where growth inhibition and symptom relief may be achieved by specific 'blocking' agents - this is particularly the case with liver metastases in well-differentiated Neuroendocrine Tumours (NETs).Spread to the liver may occur from NETs of the foregut, midgut as well as hindgut. NET metastases are usually multiple and of varying size. In most cases, both liver lobes are affected, but widespread (miliary) seeding throughout the liver is seen…
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