Tag: Watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome
The VIPoma syndrome, also called the Verner-Morrison syndrome, pancreatic cholera, and the WDHA syndrome (for watery diarrhea, hypokalemia, and achlorhydria), results from an endocrine tumor, usually in the pancreas that ectopically secretes vasoactive intestinal polypeptide (VIP). They are also commonly found in the duodenum.
Some of these tumours may be associated with MEN1 syndrome
Neuroendocrine Tumours (NETs) can sometimes present with one or more vague symptoms which occasionally results in a lengthy diagnostic phase for some. Sure, there can be issues with doctor experience and knowledge that can add to the problem. However, some people do present with multiple vague and confusing symptoms and some people have comorbidities which have similar symptoms. Textbook diagnostics just don't make sense, sometimes even when the doctor suspects a NET i.e. classic symptoms of 'something' but with negative markers for NETs. Clearly those are extreme cases and just like other complex diseases, many diagnoses of NET can be extremely challenging. Even for an experienced doctor, it can be a difficult jigsaw!Most types of NET can have associated 'syndrome' i.e. the tumours are 'functional' and this is normally (but not always)…