
What is Chromogranin A? Chromogranin A (CgA) is an acidic protein released along with catecholamines from chromaffin cells and nerve terminals. This statement alone might explain why it’s a good marker to use with Neuroendocrine Neoplasms. It is said to be a measure of tumour bulk. Depending on the test kit being used, you may […]

Diagnosing Neuroendocrine Neoplasms (NENs). It’s no secret that Neuroendocrine Neoplasms (NENs) can be difficult to diagnose, particularly well differentiated slow growing types (NETs) which can sometimes be difficult to see. Plus, many patients present with relatively routine day to day symptoms suggesting a myriad of day-to-day illnesses seen daily in every GP/PCP practice. But conversely, […]

What are Rectal NENs Rectal Neuroendocrine Neoplasms (NENs) (rNENs) account for approximately 1-2% of all primary cancers in the rectum. The other main cancer types found in the rectum are regular adenocarcinomas (the vast majority) and some other rare types including Gastrointestinal stromal tumors (GIST) and Lymphoma. The vast majority of rNENs will be well […]

A new clinical trial post. What is Terbium-161 (161Tb-DOTA-LM3) (Beta plus). Terbium-161 is a radioactive substance. DOTA-LM3 is a novel somatostatin antagonist targeted using somatostatin receptor number 2 (SSTR2). Combined they form a radioligand for use in Pepetide Receptor Radionuclide Therapy (PRRT). It’s a beta emitter but labelled ‘plus’ on the basis it offers more […]

Like many people from outside USA, I don’t really know anything about Maria Menounos. For those in the same boat, let me confirm she is a very well-known personality in USA. A journalist, television presenter and actress. She has hosted Extra and E! News; she was a TV correspondent for Today, Access Hollywood, and co-hosted […]
Love you are doing this . . . So inspirational . . . I’m a wee lass in Oregon with a type of tumor called GIST not known to be neuroendocrine but I think I just proved it is and will be changing how doctors think about my cancer (SDHB mutation dad died of paragangliomas). Love the song 500 miles . . . In January 2020 my husband and daughter (age 35) sang that song in concert in Ashland, Oregon. Little did I know COVID was about to pounce and I’d end up in hospital for emergency surgery in March the night hospital COVID shutdown started thus my husband couldn’t be with me. I played the recording of that song for the nurses and it helped get me through that terrible surgery in which I almost died. Then I had to have another surgery in October 2021 during COVID at our National Cancer Institute when the same tumor tried to kill me again. I’m also a patient advocate but for a much smaller group of patients who have the SDHB inherited/germline mutation of Gist/Para/Pheo.
Nice to hear from you again and glad you’re OK after surgery. Great story about the song!
Fantastic accomplishment! You are such an inspiration!
thanks