
This ENETS guidance paper, developed by a multidisciplinary working group, provides up-to-date and practical advice on the diagnosis and management of digestive neuroendocrine carcinoma, based on recent developments and study results. These recommendations aim to pave the road for more standardized care for our patients resulting in improved outcomes. However, it’s true to say that […]

One of the key awareness messages for Neuroendocrine Cancer is the hormonal syndromes that can often accompany the diagnosis for many people. As it’s a difficult disease to diagnose, many people struggle with these syndromes for some time before formal diagnosis of Neuroendocrine Cancer. Some continue to struggle after. Neuroendocrine Cancer can often be uncannily […]

When I first created my blog in April 2014, I had to find some material to lead up to my 84 mile walk (at the time, it was a temporary vehicle for the single purpose of raising money for charity). An idea I had probably led to the longer term survival of this blog after […]

Laughter is important. This is a remastered version of one of my early blog posts. It centred on a ‘get-well’ card I received recuperating in hospital after my first major surgery. The person who sent it knew I had a sense of humour, and it did make me smile. My surgeon’s secretary came to visit […]

The ENETS 2023 guideline for gNETs are combined with the guidelines for Duodenal NET (dNET) due to their close relationship in anatomical terms. Gastric neuroendocrine neoplasms (gNENs) are tumours with an increasing annual incidence and. The vast majority of gNENs are well-differentiated neuroendrocrine tumours (NETs), which are usually classified according to the background gastric pathology […]
I recall asking how many tumours were found in the Small Bowel. The surgeon replied there were too many to count but we removed the affected length plus a clear % at each end. The tumours had already metastasised to the liver, lymph node and the mesentery. What was fascinating was the primaries being G1 and the metastases at G2.
it would have been an interesting correlation, but I did note that there was even one patient where they spotted the same signature in different metastases from the same primary tumour!
Admittedly much of this was way over my head. I will say how grateful I was for an astute surgeon. I presented with a pretty typical NET on imaging, but when they got in there they also found a second tumor in the Ileum and the 3 multifocal mesenteric tumor deposits that were .03 cm, .08 cm, and 1 cm. The correlation between the two nets (Jejunum and Ileum which were completely separate) and the tumor deposits is confusing to me.