
Summary Great start to 2023 and I thank those who continue to support my social media and this blog. I’m keen to hear any suggestions of the sort of thing you would like me to research and publish. The top 10 most-read posts in January are listed below: Paul Hunter Tribute – Snooker champion and […]

Trial Summary This interesting trial is a multi-cancer effort including NET. The phase I clinical trial of Procaspase Activating Compound-1 (PAC-1), a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial […]

I’m behind the curve on this one after being ahead on celebrities such as Steve Jobs, Aretha Franklin, Wilko Johnson and Olivia Williams. But in my defence, Dustin Diamond was not that well known in UK. I noticed his name mentioned in relation to “Neuroendocrine” in early 2023. I set about searching and it didn’t […]

USA finally commits UK and Australian figures recently confirmed that Neuroendocrine Cancer is the 10th and 7th most common cancer type. It was great to see this post from the American Society of Clinical Oncology, albeit the USA is joining later than many other countries confirming the worst-kept secret ever – NETs are not rare. […]

What is Cancer Ablation? This is a minimally invasive surgical method to treat solid cancers. Special probes are used to “burn” or “freeze” cancers. Computed Tomography (CT), Ultrasound (US) or Magnetic Resonance Imaging (MRI) is used to guide and position the needle probe into the tumour. This requires only a tiny hole, usually less than […]
I recall asking how many tumours were found in the Small Bowel. The surgeon replied there were too many to count but we removed the affected length plus a clear % at each end. The tumours had already metastasised to the liver, lymph node and the mesentery. What was fascinating was the primaries being G1 and the metastases at G2.
it would have been an interesting correlation, but I did note that there was even one patient where they spotted the same signature in different metastases from the same primary tumour!
Admittedly much of this was way over my head. I will say how grateful I was for an astute surgeon. I presented with a pretty typical NET on imaging, but when they got in there they also found a second tumor in the Ileum and the 3 multifocal mesenteric tumor deposits that were .03 cm, .08 cm, and 1 cm. The correlation between the two nets (Jejunum and Ileum which were completely separate) and the tumor deposits is confusing to me.