Osteoclastic activity refers to the body’s process of breaking down bone in order to build it up again.
When consistent force is applied to a tooth, osteoclastic activity breaks down the bone in the jaw, allowing the tooth to move. At the same time, osteoblastic activity builds up new bone to fill in the space left behind the tooth.
Osteoclastic activity takes 48–72 hours to fully begin, but only takes about four hours to stop. This is why it’s essential for patients to wear their aligners at least 22 hours per day. When the aligners go unworn for several hours, it can take several days for the activity to start up again.
Cancer is a growth industry ...literally! More people are being diagnosed than ever before. Fortunately, more people are surviving than ever before. This is against a backdrop of better awareness, better screening in the big population cancers, and to a certain extent better diagnostic tools, all of which is leading to earlier diagnosis.So how does this affect Neuroendocrine Cancer?According to the latest SEER database figures for Neuroendocrine Cancer, one reason for the 7 fold increase in incidence rates since the 1970s is all of those things above including better diagnostics. This has led to a revised set of epidemiological information in many countries that have made the effort to accurately update their cancer registries and there are consistent reports of incidence rates way beyond the recognised rare thresholds. Another piece…