Spotlight on Cushing’s Syndrome in Neuroendocrine Neoplasms
Intro Cushing’s syndrome is one of the most challenging hormonal complications seen in people with neuroendocrine neoplasms (NENs). It can be subtle, severe, or even life‑threatening — and it is often misunderstood. Many patients struggle for months or years before receiving a correct diagnosis, partly because the symptoms overlap with everyday conditions such as weight gain, diabetes, hypertension, fatigue, and mood changes. This Spotlight aims to bring clarity. It explains what Cushing’s syndrome is, how it relates to NETs, why ectopic ACTH matters, and what recent evidence tells us about the tumours most likely to cause it. As always, the…
