What is ONC201? A company called Oncoceutics is developing a novel class of safe and effective cancer therapies called imipridones. Imipridones have a unique three-ring core structure and selectively target G protein-coupled receptors (GPCRs), the largest class of membrane receptors and a common target of approved drugs that are underexploited in oncology. Despite being historically […]
Those who know about the 5 E’s of (so called) carcinoid syndrome will get the meaning of this story straight away. For those unaware of those 5 E’s, read about them here. I sometimes need motivating and it’s really easy to put off doing ‘hard things‘, instead opting for your comfort zone of staying at […]
The news that Justice Ruth Bader Ginsburg (RBG) has been treated for ‘Pancreatic Cancer’ has hit the headlines and effectively gone viral. She is not only famous for being a member of the US Supreme Court, but also because she has had many bouts with cancer. What has also gone viral, but only in the […]
I first heard about this drug at ENETS Barcelona 2017 and then again in 2018. It’s now starting to be discussed in USA including at the 2019 ASCO conference. It was known then as Sulfatinib but for reasons unclear to me it was changed later to Surufatinib. It’s a novel, oral angio-immuno kinase inhibitor that selectively […]
No matter where you look on social media, there are millions of sites claiming that ‘this’ and ‘that’ can cure cancer. If you analyse some of the things that can apparently ‘cure’ cancer, you will normally find that behind these fantasies, there is someone selling something, a book, a video, a product. I was also […]
I offer you two subjects in one article but they are overlapping and very related. The piece of research in the 2nd half of the article is very exciting – did you know researchers have found there are two main sub-types of pNETs, one less likely to recur and metastasise than the other? This will […]
