Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Archives

Tag: Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Approximately 7% to 16% of those with SCLC will develop SIADH at some point. With SIADH, a person produces an excessive amount of antidiuretic hormone (ADH). Normally, ADH helps the kidneys control how much water the body loses through the urine. An excess amount of the hormone results in the body retaining too much water and leads to low sodium levels.

Symptoms of SIADH include:

– falls
– headache
– nausea
– seizures
– depression
– muscle cramps
– lethargy
– fatigue
– confusion
– personality changes

Patient Advocacy, Survivorship, The NET Effect SeriesEctopic Cushing’s syndrome (ECS), Neurologic paraneoplastic syndromes, Paraneoplastic syndromes, Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Paraneoplastic Syndromes – the NET Effect

By Ronny Allan Jul 28, 2020 3 Comments

Spectrum of paraneoplastic humoral syndromes secondary to NETs. CT, calcitonin; PTHrP, parathyroid hormone related peptide; CGRP, calcitonin gene related peptide; GLP, glucagon like peptide; ANP, atrial natriuretic peptide; VIP, vasointestinal peptide (*). Citation: Endocrine-Related Cancer 17, 3; 10.1677/ERC-10-0024 (* Author's note: not the usual description of VIP indicating a potential ectopic context) Although several hypotheses have been proposed regarding the pathogenesis of PNSs, the precise mechanism that leads to the development of PNS remains largely unknown. (In simple terms, pathogenesis means "the manner of development of a disease"Disclaimer. I read widely and noted various papers where there was clearly confusion…